go up in smoke 以失败告终;一事无成;被焚毁;被烧掉;被付之一炬

【例句】
It would take just one match for this whole place to go up in smoke.
只要一根火柴就能把这整个地方烧得精光。

He saw his life savings go up in smoke when the stock market crash.
股市崩盘后，他眼看毕生积蓄化为乌有。