have one's hands full，直接翻译的意思是“两只手都满了”，可以引申为“忙得不可开交”、“腾不出手来”或者“有很多事情要做”。

【例句】
I've really had my hands full, could you help me do the housework?
我已经忙得不可交了，你可以帮忙做一下家务吗？

Nowadays, many people have their hands full with study, work, kids, and have no time traveling.
现今很多人忙于学习、工作和带孩子，没有时间去旅游。