run-down形容身体支撑不住疲惫不堪了；破败的；疲惫；不景气的；失修的；衰败的；略感不适。

【例句】
He bought a run-down television station.
他买下了一个不景气的电视台。

My doctor said I was looking run-down and ought to take some time to rest.
医生说我看上去疲惫不堪，需要休息一段时间。