The hands and feet contain more sweat glands than any other part of the body. One square inch of skin on the palm of your hand may contain as many as three thousand tiny sweat glands. But not all sweat glands are the same and sweat from different parts of the body is produced in different ways. Working Hard, Getting Sweaty When you’re working hard, sweat forms mostly on your face and upper body while hands tend to sweat more under emotional strain. This is because the different sweat glands are activated in different ways. One way is through the nervous system. When you’re working hard or feeling hot, your body communicates those ideas to the brain by way of nerves. In response, the brain sends messages back along the nerves to the sweat glands, telling them to increase the operation of the body’s cooling system.