Somebody is in charge of something... 某人负责...

something be in the charge of somebody 某事被某人负责

例句：

My father is in charge of the hospital.=The hospital is in the charge of my father.

我爸爸主持这家医院的工作。

Aunt Wang is in charge of financial matters in family firm.

王阿姨在家族企业中负责财务。

露西负责冰箱的设计。

Lucy is in charge of the design of refrigerator.

露西负责冰箱的设计。

背景音乐：

Monta-I'm sorry.