take leave of your senses

take leave of 表示“失去”，“同...告别”(约等于part from)

则take leave of one's sense 表示“失去理智”“举止若狂”。

to lose your good judgment

昏了头，失去理智

You can't take the children out sailing in this weather! Have you completely taken leave of your senses?

你不能在这样的天气里带孩子们出海!你疯了吗?

Sam, have you taken leave of all your senses? We may not even return this way.

山姆，你完全丧失理智了吗?我们连回程走不走这条路都不知道。