Too many extracurricular activities will interfere with your studies.

过多的课外活动会妨碍你的学业。

interfere有干扰和妨碍的意思，如果表示妨碍某事可用interfere with something这个词组;如果表示干涉某事，则用interfere in something。

Any country is not allowed to interfere in our country's internal affairs.

任何国家都不允许干涉我国的内政。