Bottoms up!干杯!

A: This is a toast for good luck. Bottoms up!

祝大家好运，干杯!

B: Yeah, good luck, everyone!

对，祝大家好运!

I'd like to propose I make a toast to....(为...)干杯。

A: I'd like to propose a toast to the newly married couple.

我要向新婚夫妇敬酒。

B: Good luck with your marriage. You will need it!

祝你们婚姻幸福!