scream one's head off 大笑不止，笑得前俯后仰，大声狂叫

【例句】 When my mother sawthe mouse on the kitchen floor, she started screaming her head off!
当我妈妈在厨房地板上看到老鼠时，她开始尖叫起来！

In Edvard Munch'spainting, the figure is screaming his head off in despair.
在爱德华·蒙奇的画中，这个人物绝望地尖叫着。